Interleukin-18 in Health and Disease
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چکیده
منابع مشابه
Exploring the role of Th1 cytokines: interleukin-17 and interleukin-18 in periodontal health and disease.
There are conflicting data regarding the role of interleukin (IL)-17 in periodontal health and disease. However, IL-18 levels are known to increase with the severity of periodontal disease. The present study was performed to explore the role of these proinflammatory cytokines in periodontal disease progression, and also to clarify the effect of periodontal treatment on their concentration. Sixt...
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Online First articles must include the digital object identifier (DOIs) and date of initial publication. establish publication priority; they are indexed by PubMed from initial publication. Citations to may be posted when available prior to final publication). Online First articles are citable and accepted for publication but have not yet appeared in the paper journal (edited, typeset versions ...
متن کاملInterleukin 18
Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses. IL-18 is expressed at sites of chronic inflammation, in autoimmune diseases, in a variety of cancers, and in the context of numerous infectious diseases. This short review will describe the basic biology of IL-18 and thereafte...
متن کاملInterleukin-18 and IL-18 Binding Protein
Interleukin-18 (IL-18) is a member of the IL-1 family of cytokines. Similar to IL-1β, IL-18 is synthesized as an inactive precursor requiring processing by caspase-1 into an active cytokine but unlike IL-1β, the IL-18 precursor is constitutively present in nearly all cells in healthy humans and animals. The activity of IL-18 is balanced by the presence of a high affinity, naturally occurring IL...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2019
ISSN: 1422-0067
DOI: 10.3390/ijms20030649